Treatment of the increase of the weight difference in high speed tablet press machine

Treatment of the increase of the weight difference in high speed tablet press machine

Tablet is a kind of tablet or special-shaped solid preparation which is pressed after the drug and excipients are evenly mixed. Because of its simple use and convenient carrying, its market scale has been growing continuously in recent years. With the upgrading of consumption level, people's awareness of health is strengthened, and the demand for management and treatment of common diseases, frequently occurring diseases and chronic diseases is also increasing. The management and treatment of these common, frequently occurring and chronic diseases are closely related to the use of tablet drugs.

Among them, the high-speed tablet press is used to press all kinds of granular raw materials into round and special-shaped pieces, which is the basic equipment suitable for mass production. Compared with the traditional tablet press, the high-speed tablet press has higher production efficiency and more stable tablet quality. In addition, the high-speed tablet press can absorb the dust generated when the machine is running through the double dust suction device, avoid sticking and blocking, and recycle raw materials for reuse, achieving the effect of environmental protection. Therefore, it has been widely used in many fields.

In the face of the increasingly fierce market competition environment, China's high-speed candy tablet press industry is also constantly strengthening the ability of independent innovation, market vitality and innovation are constantly released. At present, the high-speed tablet press can press all kinds of granular raw materials into round tablets, which is suitable for laboratory trial production or batch production of various tablets, sugar tablets, calcium tablets, special-shaped tablets, etc. General high-speed tablet press manufacturing enterprises can also provide various shapes of molds according to customer requirements to meet different needs of users.

However, there are user reactions. In the process of using the high-speed effervescent tablet press, sometimes the difference of tablet weight increases. What's the reason? In the process of tablet pressing, the weight difference does not exceed the limit specified in the Pharmacopoeia, so it is qualified. However, in the process of tablet pressing, if there is an increase in the weight difference, the reasons and treatment methods are as follows.

First, the punch length of the tablet press is uneven, which is easy to increase the weight difference. In view of this situation, use a caliper to check each punch before use, and then use it again. In case of light weight of individual pieces, it may be due to the failure of downrush movement, resulting in less filling of particles than others. Check out individual downrush to eliminate obstacles.

Secondly, the hopper or granulator of the dry powder tablet press is blocked. It is understood that in the tablet pressing process, if the used particles are small, sticky or wet, and occasionally foreign matters such as cotton yarn head and tablets are mixed in the particles, it is easy to make the material flow blocked, reduce the particles added into the mold hole, and affect the weight of the tablet. If the user encounters the sudden reduction of the weight of the tablet, he should stop the equipment immediately for inspection.

Thirdly, particles cause the change of sheet weight. Too wet particles, too much fine powder, too large particle size difference, and insufficient lubricant in the particles can also cause the change of chip weight difference. At this time, the quality of particles should be improved.

In summary, the increase of tablet weight difference in the tablet pressing process of high-speed tablet press is mostly due to the failure or negligence of tablet press. Therefore, before and after the operation of tablet press, users should do a good job in the maintenance work, and carefully check whether there is any damage to the parts before the operation of the equipment. It is recommended in the industry that the tablet weight should be weighed once in a certain period of time (10-20 minutes), and whether the tablet weight is As required.