The Press Should Keep The Stock Like This

The Press Should Keep The Stock Like This

A chip press lamination is a stack of two pieces.Due to the sticky flush or the roll side and other reasons, the tablet stuck to the flush, when the particle filled in the mold hole and repeatedly pressed into a lamination or because the lower flush rise position is too low, the tablet can not be pushed out in time, and at the same time added to the mold hole repeated pressure.To damage the press, we should solve the problem of sticking and supporting the punch, improve the performance of molding, and eliminate the fault of the press.

The reason and treatment of loose sheet press are as follows: loose piece is to the tablet press, the hardness is not enough, the surface has hemp hole, gently pressurized with the finger is broken.

The pressure is not enough.Solution: Increase the pressure.However, for some special purposes of the large demand pressure is large, the pressure requirements to reach the pressure limit of the press or beyond the pressure limit, need to customize the corresponding specifications of the press.Too little pressure time, fast speed.Extend the compression time, increase the prepressure and reduce the speed accordingly.

The flushing length of the multiple stamping chip machine is not uniform.Solution: Adjust the punch.The active collateral punch becomes loose.To tighten.Drug crushing fineness is not fine enough, fibrous or elastic drug or oil components content more evenly mixed.Drugs can be crushed over 100 mesh screen, choose strong adhesive, appropriately increase the pressure of the tablet press, and increase the full mixing of oil drug absorbent.

The amount of adhesive or wetting agent is insufficient or improper selection, so that the particle texture is loose or the particle thickness distribution is uneven, coarse and fine grain stratification.Can choose the appropriate adhesive or increase the dosage, improve the granulation process, multiple mixing soft materials, mixed average particles and other methods to overcome.

The particle water content is too little, the excessively dry particles have large elasticity, and the drugs containing crystalline water lose more crystalline water in the process of particle drying, making the particles brittle and easy to loose the lobe.Therefore, when granulation, the water content of the particles should be controlled according to different varieties.If the particles are too dry, they can be sprayed into an appropriate amount of dilute ethanol (50% -60%), mixed and pressed into the tablet.

The nature of the drug itself.High density of the tablet, although the hardness, but can not withstand collision and shaking.Such as soda piece is often easy to produce loose piece phenomenon; small density, poor liquidity, poor compressibility, regranulation.

The fluidity of the particles is poor, and the particles filled in the middle mold hole are uneven.There are large pieces or particles, debris blocking the scraper and feed outlet, affecting the filling amount.Add more and fewer particles in the hopper.Parparticles should be added to keep the stock in the hopper.