Several Factors Affecting Tablet Hardness

Several Factors Affecting Tablet Hardness

Tablet press machine is a very common pharmaceutical machinery, which is widely used in pharmaceutical, food, chemical and other industries. There are countless tablet presses with various designs and functions on the market. However, many customers have reported that it is not easy to find a tablet press that can really compress firm tablets . Today, I will talk to you briefly about several factors that affect tablet firmness:

1. Characteristics of medicinal powder. Generally speaking, to compress a compact tablet, the powder needs to have a good particle size, not too fine, and ultrafine powder is usually difficult to be compressed into molding; secondly, the oil content of the powder should not be too high, because the oil content in the powder will affect the cohesion between the powder particles and cause the tablet to loosen. If the oil content of the powder is high, an appropriate amount of absorbent (calcium carbonate, etc.) should be added during tableting to reduce the oil content. Similarly, the moisture content of the powder should also be controlled. If the moisture content of the powder is too high, the tableting effect will also be affected. At this time, the moisture content of the powder can be controlled by moderate drying in an oven.

2.     The pressure of the tablet press. After confirming that there is no problem with the characteristics of the powder, it is necessary to check whether the pressure of the tablet press is sufficient. The pressure of Guangdong Rich Packing Machinery Tablet Press is usually between 100kn-120kn, and the maximum pressure of large-scale tablet presses can reach 400kn, which can fully meet the production requirements of large and medium-sized pharmaceutical factories and food factories.