Tablet Press Machine Tablet Weight Over The Poor Various Treatment Methods

Tablet Press Machine Tablet Weight Over The Poor Various Treatment Methods

1、 uneven distribution of coarse and fine particles, different flow rate of particles in pharmaceutical tablet press, resulting in uneven thickness of particles filled into the holes of the mold, such as coarse particles is light, fine particles is heavy.

Solution: The particles should be mixed well or sieved to remove more fine powder.

2、If there is fine powder adhering to the punch and cause the hanging punch can make the difference of the weight of the tablets is bigger.

Solution: pharmaceutical tablet press machine at this time the lower punch rotation is not flexible, should be checked in time, remove the punch mold, clean up the lower punch and the hole in the mold.

3、Granule fluidity is not good, the amount of granules flowing into the hole of the center mold is more or less, resulting in a large difference in the weight of the tablets and exceed the limit.

Solution: Re-granulation or adding suitable flow aids such as micronized silica gel, etc., to improve the fluidity of particles.

4、Particle layering.

Solution: layering of particles to reduce the size difference.

5、Smaller tablets choose larger particles of material.

Solution: choose the appropriate size of the particles.

6, the charging bucket is blocked, this phenomenon often occurs in viscous or moisture-inducing strong drugs.

Solution: Unclog the hopper, keep the tablet pressing environment dry, and add appropriate flow aids to solve the problem.

7、Difference in the amount of material stored in the material is large.

Solution: control within 50%.

8, the doser is not balanced or not installed in place, resulting in uneven filler.

Solution: balance the feeder or installed in place.

9, scraping board is not flat or poorly installed. Solution: leveling.