The development history of tablet press machine

Tablet presses appeared earlier in Europe and America, and have a history of nearly a hundred years. Tablet presses and tableting technology are the most common and important in the pharmaceutical industry. Although tablet presses have appeared since the beginning of the 19th century (Germany Korsch, British Manesty, and Belgian Courtoy have a history of more than 80 years). In the 21st century, new tablet presses and tableting technologies are still emerging. In China, until 1949, the Shanghai factory imitated the British-style 33 punching tablet machine; in 1951, it was transformed into a domestically-made 18 punching tablet machine based on the American 16 punching tablet machine, which was a domestic-made Z model early pharmaceutical machinery; 1957 , Designed and manufactured the ZP25-4 type tablet press; in 1960, successfully designed and manufactured the 60-30 type tablet press, which has the functions of automatic rotation and tablet compression. The types of compression include tablets, sugar tablets, calcium tablets, coffee tablets Wait. In the same year, ZP33 and ZP19 tablet presses were also designed and manufactured.

In the 1970s, Shanghai diyi Pharmaceutical Machinery Factory and Shandong Medical Equipment Factory began to mass produce ZP series tablet presses as designated manufacturers of tablet presses. Later, the HZP26 high-speed tablet press was successfully developed. In 1980, Shanghai diyi Pharmaceutical Machinery Factory designed and manufactured the ZP-21W tablet press, which reached the international advanced level in the early 1980s and was the first domestic product. In 1987, the company introduced the microcomputer control technology of the Federal German Fette Company to design and manufacture the P3100-37 rotary tablet press, which has the functions of automatic control of tablet weight, pressure, automatic counting, and automatic rejection of waste tablets. The closed structure is tight and clean. The degree meets GMP requirements. In 1997, Shanghai Pharmaceutical Machinery Co., Ltd. developed the ZP100 series rotary tablet press and the GZPK100 series high-speed rotary tablet press.

In the 21st century, with the deepening of GMP certification, ZP series rotary tablet presses that fully comply with GMP have appeared one after another: ZP3, ZP35D, etc. The high-speed rotary tablet press has made great progress in the production, pressure signal collection, waste rejection and other technologies. The output of Zgao is generally greater than 300,000 tablets/hour, the Zda pre-pressure is 20kN, and the Zda main pressure is 80kN or more than 100kN. For example, the zp-27D and zp-29D of Guangdong Ruiqi Packaging Machinery Co., Ltd. are equipped with pre-compressed rails, and the number of tablets is increased, which can suppress materials that are difficult to form