Why Do Splits Occur During The Operation Of The Tablet Press?

Why Do Splits Occur During The Operation Of The Tablet Press?

The tablet falls off after it is pushed out in the die hole of the tablet press machine, which means lobes. The reason why the lobes occur is mostly because there is too much fine powder in the granules. When the tablet press is compressed, there is air in the granules, and the speed of compression is relatively Fast, the gap between the punch and the die hole is relatively small, and the air is not excluded from the particles during compression, and is enclosed in the sheet. When there is no pressure, the air will expand, which will cause splits.

According to the above situation, we should first make a pre-pressing device for the fine powder in the granules, so that the air may escape. However, many situations are unexplainable. The tablet press machine will crack when the pressure is relatively high. Reducing the pressure during tablet pressing can prevent cracking. If the particles are too dry, cracking will occur, so the water content also plays a role. key role. The reason for the fragmentation of the tablet press is the improper compression behavior of the granules. The elasticity of the granules is relatively strong, and the elasticity of the pressed tablets is relatively high, which will also cause uneven pressure.

When the rotary tablet press presses the tablet, the upper and lower pressure of the tablet is relatively large. The pressure is related to the elastic recovery rate of the tablet. The elastic recovery rate of the upper and lower surfaces of the tablet is relatively high, and the upper surface of the tablet is relatively high. Move out of the mold hole first so it will crack first.

Scientifically designed prescriptions can prevent the phenomenon of splitting. How to increase the plasticity of excipients and the formability of granules? Adding compressible starch in the process can solve the above problems.

The possibility of splitting when the pressure decreases during the pressing process of the tablet press is also small, and the recovery rate is also small. The compression time is increased and the plasticity is also increased. This can prevent the splitting phenomenon, and the water content in the granules can be determined. Shape the plasticity of the particles, improve the distribution of pressure and prevent the phenomenon of splitting. A good lubricant can also be added to change the pressure distribution and prevent splintering.Why do splits occur during the operation of the tablet press?

The tablet falls off after it is pushed out in the die hole of the tablet press machine, which means lobes. The reason why the lobes occur is mostly because there is too much fine powder in the granules. When the tablet press is compressed, there is air in the granules, and the speed of compression is relatively Fast, the gap between the punch and the die hole is relatively small, and the air is not excluded from the particles during compression, and is enclosed in the sheet. When there is no pressure, the air will expand, which will cause splits.

According to the above situation, we should first make a pre-pressing device for the fine powder in the granules, so that the air may escape. However, many situations are unexplainable. The tablet press machine will crack when the pressure is relatively high. Reducing the pressure during tablet pressing can prevent cracking. If the particles are too dry, cracking will occur, so the water content also plays a role. key role. The reason for the fragmentation of the tablet press is the improper compression behavior of the granules. The elasticity of the granules is relatively strong, and the elasticity of the pressed tablets is relatively high, which will also cause uneven pressure.

When the rotary tablet press presses the tablet, the upper and lower pressure of the tablet is relatively large. The pressure is related to the elastic recovery rate of the tablet. The elastic recovery rate of the upper and lower surfaces of the tablet is relatively high, and the upper surface of the tablet is relatively high. Move out of the mold hole first so it will crack first.

Scientifically designed prescriptions can prevent the phenomenon of splitting. How to increase the plasticity of excipients and the formability of granules? Adding compressible starch in the process can solve the above problems.

The possibility of splitting when the pressure decreases during the pressing process of the tablet press is also small, and the recovery rate is also small. The compression time is increased and the plasticity is also increased. This can prevent the splitting phenomenon, and the water content in the granules can be determined. Shape the plasticity of the particles, improve the distribution of pressure and prevent the phenomenon of splitting. A good lubricant can also be added to change the pressure distribution and prevent splintering.